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About St. Joseph Health

SJH provides a full range of care facilities including 16 acute care hospitals, home health agencies, hospice care, outpatient services, skilled nursing facilities, community clinics and physician groups. All of our hospital and home health entities are accredited by the Joint Commission. In our award-winning facilities, SJH maintains a "continuum of care," matched to the diverse needs of the urban centers, smaller cities and rural communities who depend on us every day.

Brian D. Acacio, MD

  • Reproductive Endocrinology and Infertility
Additional Language Spoken
Medical Groups & Affiliations
  • Acacio Fertility Center
  • Acacio Fertility Center Inc.
27882 Forbes Road
Suite 200
Laguna Niguel, CA 92677
Accepting New Patients

Primary Office

27882 Forbes Road
Suite 200
Laguna Niguel, CA 92677
Get Directions
(949) 249-9200
(949) 249-9203

More Information

  • Meet The Doctor

    Specialties & Education

    Primary Specialties
    • Reproductive Endocrinology and Infertility
    Education & Training
    • Medical School
      George Washington University- School of Medicine
    • Internship
      LAC- USC Medical Center
    • Residency
      LAC- USC Medical Center
    • Fellowship
      LAC-USC Medical Center Women's Hospital - 1999
    Areas of Interest
    Reproductive Endocrinology
  • Biography


    Patients describe Dr. Acacio as being personable, kind and encouraging. His dedication to excellence and compassionate care is motivated by his passion for what he loves doing best: helping patients attain their dream of parenthood. He is frequently named among the top reproductive endocrinologists in California and the United States.

    Dr. Acacio has had some of the highest IVF success rates in Southern California. His outstanding academic credentials and extensive clinical experience have been vital in achieving major breakthroughs and successes in many challenging cases that have experienced IVF failure in prior treatments. Highly respected by his peers, Dr. Acacio is often consulted by other physicians who come to him for infertility evaluation and treatment.

    He received a Vitals Most Compassionate Doctor Award in 2010 and a Patients Choice Award in 2014 and was a “Top Doctor” in Orange Coast Magazine in 2016. U.S. News & World Report has also recognized Dr. Acacio among the top 10% of reproductive endocrinologists in the country.

    Dr. Acacio has been actively involved in teaching and training other physicians over the years. He is the division head of REI in the Department of Obstetrics and Gynecology at Kern Medical Center in Bakersfield, having trained OB/GYN resident physicians there for over 11 years. Residents in California's Central Valley can now receive convenient care at his satellite office in Bakersfield.

    Dr. Acacio is active in research and has over 50 publications and lectures in nationally recognized peer-review journals and conferences. He has been featured in interviews on National Public Radio (NPR) and several local news stations. He serves as a director on the Board for Fertile Action.

    Dr. Acacio is licensed to practice medicine in California. He has medical staff privileges at some of the leading hospitals throughout Southern California, including Mission Hospital (where he volunteered and worked in the pharmacy as a youth), Kern Medical Center and Mercy Southwest Hospital.

    On a personal note, Dr. Acacio enjoys surfing, golf, art, reading, traveling and spending time with his wife and two daughters.
    American Board of Obstetrics & Gynecology American Board of Obstetrics & Gynecology