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About St. Joseph Health

SJH provides a full range of care facilities including 16 acute care hospitals, home health agencies, hospice care, outpatient services, skilled nursing facilities, community clinics and physician groups. All of our hospital and home health entities are accredited by the Joint Commission. In our award-winning facilities, SJH maintains a "continuum of care," matched to the diverse needs of the urban centers, smaller cities and rural communities who depend on us every day.

William Shankle, MD

  • Neurology
    (Board Certified)
Additional Language Spoken
Medical Groups & Affiliations
  • Hoag Affiliated Physicians
  • Hoag Physician Partners
Shankle Clinic
3900 West Coast Highway
Suite 310
Newport Beach, CA 92663
Accepting New Patients

Primary Office

Shankle Clinic
3900 West Coast Highway
Suite 310
Newport Beach, CA 92663
Get Directions
(949) 478-8858
(949) 242-2465

More Information



  • Meet The Doctor

    Specialties & Education

    Primary Specialties
    • Neurology
      (Board Certified)
    Education & Training
    • Medical School
      Brown University - 1983
    • Internship
      Cook County Medical Center
    • Residency
      University of Southern California
  • Biography


    Dr. Shankle is a board certified neurologist, specializing in the diagnosis, treatment and management of Alzheimer’s disease and related disorders (ADRD). He co-founded the Alzheimer’s Research Center at University of California, Irvine, in 1987 and served as its clinical director for 10 years. Following that endeavor, he initiated a community based ADRD program, the Shankle Clinic, in 1997 to deliver his medical knowledge to a broader community of patients and families.

    As the director of the Memory and Cognitive Disorders program at Hoag Neurosciences Institute, Dr. Shankle works with and enables primary care physicians to identify and manage an individual’s risk factors for ADRD. Under Dr. Shankle’s guidance, the program also provides the support of a comprehensive triage and clinical research team, utilizing the most sensitive cognitive assessment tool to detect the first stage of mild cognitive decline leading to development of Alzheimer’s disease, and tailors the best possible prevention and treatment options for each individual.

    He currently maintains his academic career at the Department of Cognitive Sciences at the University of California, Irvine. He also holds additional responsibilities as a member of the grant review committee for the National Alzheimer’s Association, and as a journal reviewer for ADRD related journals.

    Dr. Shankle is a recipient of many research grants and awards including the Zenith Fellows Award from the Alzheimer’s Association that is given to those who have contributed significantly to the field of Alzheimer’s disease research. In addition, his findings on human brain development were reported by The New York Times to be one of the most important scientific discoveries of the 1990s. He is also a co-author of various neuroscience textbooks as well as “Preventing Alzheimer’s” (Putnam Press 2004/2007).

    Dr. Shankle received his bachelor degree in Biology from Stanford University and his M.D. from Brown University. He trained as a statistician at the University of Southern California with postgraduate studies at Harvard. He completed his internship in internal medicine at Cook County Hospital, and his residency in neurology at LA County/USC Medical Center.
    Areas of Expertise
    Alzheimer's disease, Memory and Cognitive disorders
  • More Info

    More Info