Harikrishna J. Makani, MD

4.6 out of 5 (133 Ratings)
  • Cardiology
  • Interventional Cardiology
Additional Language Spoken
Hindi, English
Medical Groups & Affiliations
  • Premier Healthcare
  • St. Mary High Desert Medical Group
St. Mary High Desert Apple Valley - Cardiology and Pulmonology
19341 Bear Valley Road
Suite 105
Apple Valley, CA 92308
Accepting New Patients

Primary Office

St. Mary High Desert Apple Valley - Cardiology and Pulmonology
19341 Bear Valley Road
Suite 105
Apple Valley, CA 92308
Get Directions
(760) 247-6444
(760) 247-6559
Mon - Fri: 8 a.m. - 4:30 p.m.

More Information

  • Meet The Doctor

    Specialties & Education

    Primary Specialties
    • Cardiology
    • Interventional Cardiology
    Secondary Specialties
    • Internal Medicine
    Education & Training
    • Medical School
      B J Medical College, Gujarat University - 2005
    • Internship
      St. Luke's Roosevelt - 2007
    • Residency
      St. Luke's Roosevelt - 2008
    • Fellowship
      St. Luke's Roosevelt - 2010
    Areas of Interest
    Cardiology, Interventional Cardiology, Internal Medicine
  • Biography



    Dr. Harikrishna Makani is a board certified Interventional Cardiologist with St Mary High Desert Medical Group serving patients at St. Mary Medical Center. Dr. Makani brings a strong background in the field of Hypertension, Hypertrophic cardiomyopathy (thick heart muscle disease), stress echocardiography and advanced interventional cardiology techniques to St. Mary High Desert Medical Group.

    Dr. Makani is an internationally recognized name in the field of hypertension. He has authored or co-authored more than 50 journal publications, book chapters and abstract publications in top medical journals like Journal of American College of Cardiology, British Medical Journal and European Heart Journal. He has also received numerous awards like Young Investigator Award in American Society of Hypertension meeting, Best research award at Annual research fair award at St. Luke’s Roosevelt hospital to name a few, for his research accomplishments. His research focus mirrors his clinical practice: He looks at care of patients with hypertension, coronary artery disease, heart attack or chest pain, heart failure, complex angioplasties, and peripheral vascular disease.

    A specialist in cutting-edge minimally invasive procedures such as transradial angioplasty to treat coronary artery disease, Dr. Makani offers procedures that, while still less common at many U.S. hospitals, promise quicker recovery compared to standard methods. For example, he performs transradial angioplasty, which uses a patient’s wrist instead of the groin as the incision point and has a much lower rate of bleeding and faster recovery time.

    Dr. Makani is board certified in Internal Medicine, Cardiovascular Diseases, Nuclear Cardiology, and Echocardiography and is a Registered Physician in Vascular Interpretation.

  • 19-Apr-2020
    Today (*) I had to call Makani's office for refill of _____ I asked for last week! This is a heart med so why is it taking so long?? I was calling out meds I needed to his back when he "finished" his 5 mins. on * appt. I could only get my meds renewed in time if he actually listened to me or my list I gave him most of them are for heart problems. I wasn't given a mask to wear & 3 days later I had COVID-19, he didn't care about that! I also need a direct message phone for *Lisa Morales, NP - I need copies of ALL my labs.
    I would say this visit was very good,the issue was about my medicaion I was takeing for gonjestive heart failure. I was haveing itching all over my body from my ankled to my shoulders and moving from one location to another .the doctor assured that is not the case he did tell me to stop the med for now and only use it when I start to gaine weight. we went over my records,it was very good visit thank you
    *Dr. Makani and his office are always very efficient and caring for myself and my husband.
    I have always had excellent service from *Dr. Makani he is very knowledgeable treating my heart condition BEFORE and AFTER my surgery.
    Dr.Mac explained what my future pacemaker experience would be to my complete satisfaction.
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